Cerebral blood flow in the four-vessel occlusion rat model.

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Cerebral Blood Flow in the Four-Vessel Occlusion Rat Model

are most likely a result of MCA occlusion. For most old rats, the thicker skull requires more drilling, and connective tissue about the vessel presents more resistance to dissection of the MCA making hemorrhage more likely than in younger rats. While the smaller lesions in older rats (734-852) are larger (p < 0.05) than for the younger rats (752-842), the size difference may be due to more surg...

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Cerebral blood flow in the four-vessel occlusion rat model.

are most likely a result of MCA occlusion. For most old rats, the thicker skull requires more drilling, and connective tissue about the vessel presents more resistance to dissection of the MCA making hemorrhage more likely than in younger rats. While the smaller lesions in older rats (734-852) are larger (p < 0.05) than for the younger rats (752-842), the size difference may be due to more surg...

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Cerebral ischemia produced by four-vessel occlusion in the rat: a quantitative evaluation of cerebral blood flow.

Cerebral ischemia was produced in the rat by simultaneous occlusion of the vertebral and carotid arteries according to the method of Pulsinelli and Brierley (Stroke 10: 267, 1979). Local cerebral blood flow (CBF) was determined by polarographic and autoradiographic techniques. Hydrogen-clearance measurements showed that mean CBF fell in four monitored regions of the hemispheres to between 0.11 ...

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Local cerebral blood flow autoregulation following "asymptomatic" cerebral venous occlusion in the rat.

OBJECT Maintenance of cerebral blood flow (CBF) autoregulation in the brain is of major importance for patient outcome in various clinical conditions. The authors assessed local autoregulation after "asymptomatic" cortical vein occlusion. METHODS In Wistar rats, a single cortical vein was occluded photochemically by using rose bengal and fiberoptic illumination. In rats with bilateral carotid...

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Local cerebral blood flow in a rat cortical vein occlusion model.

The symptoms following sinus and vein occlusion observed in patients and experimental animals display a considerable variability that so far remains largely unexplained. In a rat cortical vein occlusion model using a photochemical thrombotic technique, we examined changes in the cerebral venous flow pattern by fluorescence angiography and regional cerebral blood flow (rCBF) and cerebral blood v...

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ژورنال

عنوان ژورنال: Stroke

سال: 1984

ISSN: 0039-2499,1524-4628

DOI: 10.1161/str.15.3.579a